Step 2 of Critric Acid Cycle


Very good!! In this step, CITRATE went through a rearrangement (isomerization) reaction yields ISOCITRATE





ISOCITRATE will be our reactant for step 3, but that's not all. We need additional reactant(s) for the next reaction to proceed.



Choose the additional reactant(s) and the type of reaction that will give us ALPHA-KETOGLUTARATE, NADH, and CO2 as the result of products



CoA-SH, NAD+: Oxidation Reaction
NAD+: Oxidative Decarboxylation
FAD+: Oxidative Decarboxylation